Important Safety Information for Apidra® (insulin glulisine injection) SoloStar® Apidra (insulin glulisine injections) SoloStar® pens are a disposable single-patient-use prefilled insulin pen. It’s important to review any associated leaflets that are included with the pen and speak with your healthcare provider prior to usage to ensure proper injection technique are being followed. Important Safety Information for Apidra when used in a pump Every 48 hours the infusion sets (reservoir, catheter and tubing) and the Apidra should be replaced. Do not dilute or mix Apidra when used inside the pump which can cause degradation of the insulin and potentially cause ketoacidosis or hyperglycemia. Do carry a spare form of insulin administration in case there is a failure with the insulin pump. The information provided is for general education purposes only. You should always seek a professional healthcare professional if you have any questions and for instructions on the proper administration of Apidra insulin.

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Apidra is a fast-acting insulin that is commonly used by adults and children ( with diabetes mellitus, even for children less than 4 years old with type 1 or type 2 diabetes. Prescription Apidra is can be used to safely and effectively treat diabetes by controlling blood sugar levels.

When used Apidra as a mealtime insulin, it should be taken 15 minutes before meal time or 20 minutes after starting a meal

Prescription Apidra can be used subcutaneously by external insulin infusion pumps.

Apidra Insulin

Apidra Cartridge


Apidra Insulin

Apidra SoloStar Pens


Apidra Insulin

Apidra Vials


If you have low blood sugar reactions or have an allergic reaction to insulin glulisine (or any ingredients in Apidra) you should not use Apidra. Under any circumstances should you ever share needles and do not reuse needles. Sharing needles can lead to spreading infections and/or disease. Never inject in the same spot as this can lead to lumpy, tender, bruise, thickened, pitted, scarred or damaged skin. When injecting Apidra, you should rotate injection sites for each dose to reduce the risk of any pitted or thickened skin (lipodystrophy) or getting lumps on the skin (cutaneous amyloidosis). Always speak with a doctor before starting an insulin regimen such as Apidra. It’s important to consult your physician about any known medical conditions such as liver or kidney problems. For women looking to get pregnant or are pregnant, breastfeeding or planning to breast feed, speak to your doctor before taking Apidra. Taking Apidra with medications known as TZD (thiazolidinediones) can lead to heart failure even for those who do not have a history of heart problems. Consult a physician if you have any heart issues while taking TZD’s with Apidra to change or stop your regimen. Speak with your doctor if you are experiencing any of the following while taking Apidra insulin: Sudden weight gain Shortness of breath Swelling of feet or ankles Notify your doctor about all current medications including vitamins, supplements (herbal included) and OTC medicines. As mentioned previously, when taking Apidra or shortly after starting a meal, do test your blood sugar levels as directed by your physician. Notify your doctor if you alter dosages as this decision should be made with extreme caution and only under medical supervision. Review insulin labels to ensure that you have the correct medication before your first injection. Inspect the vial to ensure that it is clear, colorless and does not have any visible particles. Do not drive or operate heavy machinery while using Apidra until you understand its effects and how your body responds. Do not consume alcohol or medications that may contain alcohol while using Apidra. When taking Apidra, it should be known that serious side effects which can lead to death include: Hypoglycemia (low blood sugar). Symptoms and signs of low blood sugar can include dizziness or light-headedness, headache, blurred vision, sweating, confusion, increased heartbeat, anxiety, slurred speech, shaking, hunger and mood changes. If you experience serious allergic reactions, immediately consult a doctor right away. This may include having a rash over your hole body, trouble breathing, shortness of breath, sweating, feeling faint or low potassium in blood (hypokalemia). Your physician should monitor your body for low blood glucose or potassium levels.